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422 21st St, Denver, CO 80205
422 21st St, Denver, CO 80205
422 21st St, Denver, CO 80205
422 21st St, Denver, CO 80205
422 21st St, Denver, CO 80205
422 21st St, Denver, CO 80205
422 21st St, Denver, CO 80205

422 21st St Denver, CO 80205

$1,200,000

PENDING
Beds
4
Baths
2
Sqft
6,565
Acres
0.14
Year
1886
Days on Site
52
Property Type
Residential
Sub Type
Single Family
Per Square Foot
$183
Date Listed
Feb 10, 2026

Description of 422 21st St, Denver, CO 80205

Listing details for 422 21st St, Denver, CO 80205 : Located in the heart of Five Points, this unique for-sale offering presents a compelling investment, owner-user, or redevelopment opportunity on a highly visible 6,270 SF corner lot just steps from Downtown Denver, Uptown, and the vibrant Five Points district. The property consists of a well-maintained single-family home and an adjacent office duplex, providing multiple income streams and flexible future potential. The approximately 2,565 SF single-family residence features four bedrooms and two bathrooms and is most recently operated as a successful Airbnb, offering immediate short-term rental income or the option for an owner-user residence. The office duplex is comprised of two office units of approximately 2,000 SF each, both tenant-occupied on month-to-month leases, allowing for steady income with near-term flexibility for repositioning or redevelopment. With its premier corner location, walkability to Denver’s central business district, and proximity to restaurants, nightlife, transit, and cultural amenities, this property offers exceptional upside in one of Denver’s most dynamic and rapidly evolving neighborhoods.
Listing Updated : 03-27-2026 at 8:46 AM MDT
Listing Provided By : Karen Zeile, 303-773-3399, Kentwood Commercial, Llc
Source :

recolorado as distributed by MLS GRID, MLS#: REC6487194

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Based on information submitted to the MLS GRID as of 2026-04-03 at 11:31 a.m. MDT. All data is obtained from various sources and may not have been verified by broker or MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information.

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